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The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Brenton, Dr James james.brenton**[ta]**k.cam.ac.uk

CRUK/10/030: TRICON8 - Sample collection of ovarian cancer tissues and blood for translational research from patients participating in the CR-UK/MRC ICON8 trial University of Cambridge 01/01/2013 31/12/2015 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Personalised biomarkers of response in high-grade serous ovarian cancer University of Cambridge 01/04/2013 31/03/2018 Science Committee - Programme Award Science Committee

Functional genomics of ovarian cancer Cancer Research UK Cambridge Institute 01/10/2011 30/09/2016 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Bridgewater, Professor John j.bridgewater**[ta]**.ac.uk

CRUK/13/012: Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma (ACTICCA-1 trial) (supported by Stand Up To Cancer) University of Birmingham 01/04/2015 30/09/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Brierley-Jones, Dr Lyn Direct2Deaf: Cancer Prevention In BSL (British Sign Language) University of Sunderland 01/03/2015 29/02/2016 Population Research Committee - BUPA Foundation Fund - Innovation Grant Population Research Committee

Brindle, Professor Kevin kmb1001**[ta]**.ac.uk

The CRUK & EPSRC Cancer Imaging Centre in Cambridge & Manchester University of Cambridge 01/12/2013 30/11/2018 Scientifc Executive Board - Cancer Imaging Centres Scientifc Executive Board

Molecular Imaging Groups Cancer Research UK Cambridge Institute 01/04/2014 31/03/2019 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Brock, Dr Penelope CRUK/07/023: SIOPEL 6: A randomised phase III trial of the efcacy of sodium thiosulphate in reducing ototoxicity in patients receiving cisplatin chemotherapy for hepatoblastoma University of Birmingham 01/04/2007 31/12/2015 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Brognard, Dr John Signalling Networks in Cancer Cancer Research UK Manchester Institute 01/08/2010 31/07/2017 Biological Sciences Committee - Institute Group Award Science Committee

LZK: A Novel Target for Therapeutic Intervention in Head and Neck Squamous Cell Carcinoma University of Manchester 01/03/2015 28/02/2017 Science Committee - Drug Discovery Project Award Drug Discovery Committee

Brown, Dr Jamie jamie.brown**[ta]**.ac.uk

The ‘real-world’ associations between e-cigarette use and smoking cessation: A prospective cohort study University College London 01/03/2015 31/05/2017 Tobacco Advisory Group - Project Award Tobacco Advisory Group

Brown, Professor Janet Exploratory and preclinical development and a Phase I frst in human clinical study to evaluate the biological effects of Ad[I/PPT-E1A] Trojan macrophage virotherapy in prostate cancer University of Shefeld 01/07/2015 30/06/2020 New Agents Committee - DD Project Proposal New Agents CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Brown, Professor Julia j.m.b.brown**[ta]**ds.ac.uk

Clinical Trials and Advisory Committee (CTAAC) Clinical Trials Fellowship: Leeds Clinical Trials Research Unit application University of Leeds 01/07/2015 30/06/2018 Clinical Trials Awards & Advisory Committee - Clinical Trial Fellowship Clinical Trials Awards & Advisory Committee

Brown, Professor Karen kb20**[ta]**ac.uk

Biomarker-driven development of cancer chemopreventive agents: a new paradigm University of Leicester 01/07/2011 30/09/2016 Science Committee - Programme Award Science Committee

Brown, Professor Robert b.brown**[ta]**erial.ac <mailto:b.brown**[ta]**erial.ac>.uk

Mechanisms of Drug Resistance and Epigenetic Regulation Imperial College London 01/10/2011 30/09/2016 Science Committee - Programme Award Science Committee

Bryan, Dr Richard r.t.bryan**[ta]**nternet.com CRUK/11/027: The collection of biospecimens from patients eligible for the "POUT" clinical trial in upper urinary tract urothelial carcinoma University of Birmingham 01/02/2014 31/01/2024 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Bubeck, Dr Doryen d.bubeck**[ta]**erial.ac.uk

A structural approach to visualising complementmediated pore-formation Imperial College London 01/01/2014 31/12/2019 New Investigator Committee - Career Establishment Award New Investigator Committee

Buczacki, Mr Simon Simon.Buczacki**[ta]**k.cam.ac.uk

Manipulating the quiescent cancer stem cell niche in colorectal cancer University of Cambridge 01/10/2013 30/09/2017 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Burchill, Professor Susan s.a.burchill**[ta]**ds.ac.uk

Qualifcation of target mRNAs as prognostic and predictive biomarkers in children with high-risk neuroblastoma University of Leeds 01/09/2014 31/08/2018 Science Committee - Biomarker Project Award Science Committee

Burke, Dr Gladstone amos.burke**[ta]**enbrookes.nhs.uk

CRUK/11/038: Intergroup trial for children or adolescents with B-cell NHL or B-AL: evaluation of rituximab efcacy in high risk patients (Inter-B-NHL ritux 2010) University of Birmingham 01/11/2012 31/10/2022 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Burn, Professor Sir John john.burn**[ta]**.ac.uk

CRUK/12/039: CaPP3 - a double blind randomised controlled dose inferiority trial of aspirin prevention in people with Lynch syndrome: high risk of cancer due to mutations in the mismatch repair genes (supported by Stand Up To Cancer) Newcastle University 01/09/2013 31/08/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Burnet, Professor Neil Distinguishing physical and biological determinants of radiotherapy toxicity (Vox Tox).University of Cambridge 01/06/2012 31/05/2017 Clinical and Translational Research Committee - Programme Award Science Committee

Buykx, Dr Penny p.f.buykx**[ta]**feld.ac.uk

To investigate public knowledge of the link between alcohol and cancer and to examine public attitudes towards alcohol policy University of Shefeld 01/06/2015 31/03/2016 Tobacco Advisory Group - Commissioned Research Tobacco Advisory Group

Calado, Dr Dinis Immunity and Cancer The Francis Crick Institute 01/03/2013 28/02/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive BoardCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Caldas, Professor Carlos carlos.caldas**[ta]**k.cam.ac.uk

Trans-PERSEPHONE and Trans-PERSEPHONE-SNPs: the pharmacogenomics and pharmacogenetics of adjuvant trastuzumab.University of Cambridge 01/04/2008 31/03/2016 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Breast cancer genomics Cancer Research UK Cambridge Institute 01/06/2013 31/05/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Caldecott, Professor Keith k.w.caldecott**[ta]**sex.ac.uk

Non-homologous End-Joining Protein Complexes and Genome Stability University of Sussex 01/05/2014 30/04/2019 Science Committee - Programme Award Science Committee

Callister, Dr Matthew matthew.callister**[ta]**dsth.nhs.uk

reSEARCH: A biorepository to provide RE agents for the discovery of molecular predictors of lung tumour development, collected in the Lung-SEARCH trial University of Leeds 01/10/2007 31/03/2016 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Calton, Dr Elizabeth elizabeth.calton**[ta]**.ac.uk

Determining the Clonality of Stage 4S Neuroblastoma Institute of Cancer Research 01/02/2015 31/10/2015 Clinical Careers Committee - Research Bursary Clinical Careers Committee

Cameron, Professor David d.cameron**[ta]**ac.uk

CRUK/13/010: UNIRAD Sample Collection Institute of Cancer Research 01/08/2015 31/07/2020 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Campbell, Dr Christine christine.campbell**[ta]**ac.uk

The influence of a negative FOBT on the response of screening invitees and healthcare providers to symptoms of colorectal cancer.University of Edinburgh 01/07/2012 30/09/2015 National Awareness and Early Diagnosis Initiative - Project Award National Awareness and Early Diagnosis Initiative

An enhanced role for primary care in bowel cancer screening: development and testing of a brief intervention for non-responders University of Edinburgh 01/04/2013 31/10/2015 National Awareness and Early Diagnosis Initiative - Project Award National Awareness and Early Diagnosis Initiative

Campbell, Professor Frederick f.c.campbell**[ta]**.ac.uk

Vitamin D regulation of growth control biomarkers in human colon and colorectal cancer (CRC) Queen's University Belfast 01/01/2013 31/12/2017 Science Committee - Biomarker Project Award Science Committee

Cardwell, Dr Chris c.cardwell**[ta]**.ac.uk

A novel, integrated, bioinformatics and pharmacoepidemiology approach to identifying and testing medications with potential breast cancer carcinogenicity, or anti-cancer properties Queen's University Belfast 01/09/2014 31/08/2017 Population Research Committee - Project Award Population Research Committee

Carroll, Dr Jason jason.carroll**[ta]**k.cam.ac.uk

Nuclear Receptor Transcription Laboratory Cancer Research UK Cambridge Institute 01/10/2010 30/09/2015 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Cass, NULL Suzanne 'Towards a smoke-free generation' - building on ASH Wales's collaborative tobacco control campaigns programme This project will be led by ASH Wales's Head of Communications and Public Affairs Action on Smoking and Health (Wales) 01/08/2014 31/07/2016 Tobacco Advisory Group - Project Award Tobacco Advisory GroupCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Cathcart, Mr Paul p.cathcart**[ta]**l.ac.uk

CRUKE/13/030: PROVENT - A randomised, double blind, placebo controlled feasibility study to examine the clinical effectiveness of aspirin and/or Vitamin D to prevent disease progression in men on Active Surveillance for low risk prostate cancer Queen Mary, University of London 01/07/2014 30/06/2017 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

Cerundolo, Professor Vincenzo vincenzo.cerundolo**[ta]**.ox.ac.uk

Development of vaccination strategies to enhance tumour specifc immune responses University of Oxford 01/01/2015 31/12/2019 Science Committee - Programme Award Science Committee

Chalmers, Professor Anthony anthony.chalmers**[ta]**sgow.ac.uk

CRUKE/13/034: PARADIGM: OlaPArib And RADiotherapy In newly-diagnosed GlioblastoMa (AZ/ NCRN) University of Glasgow 01/02/2014 31/01/2018 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

Identifying and validation of novel targets for overcoming radiation resistance of glioblastoma stem cels under normoxia and hypoxia University of Glasgow 01/02/2015 31/01/2017 Drug Discovery Committee - CRUK & BHC Drug Discovery Project Award Drug Discovery Committee

Chambers, Dr Anna The function of the Irc5 subfamily of chromatin remodelling enzymes in DNA repair.University of Bristol 01/10/2014 30/09/2020 New Investigator Committee - Career Development Fellowship New Investigator Committee

Chambers, Dr Stephanie stephanie.chambers**[ta]**sgow.ac.uk

Growing Grandchildren University of Glasgow 01/10/2014 31/12/2015 Population Research Committee - BUPA Foundation Fund - Innovation Grant Population Research Committee

Chesler, Dr Louis louis.chesler**[ta]**.ac.uk

Targeting the ALK-F1174L tyrosine-kinase mutation in treatment refractory neuroblastoma.Institute of Cancer Research 01/04/2013 31/03/2016 Biological Sciences Committee - Project Award Science Committee

Improving outcomes for childhood neuroblastoma - development of therapeutics targeting MYCN, ALK and tumour-initiating pathways Institute of Cancer Research 01/04/2015 31/03/2020 Science Committee - Programme Award Science Committee

Chester, Professor John ChesterJD**[ta]**diff.ac.uk

CRUK/08/015: TOTEM: A Phase I/II trial of the mTOR inhibitor temsirolimus (CCI-779; Torisel) plus Cisplatin and Gemcitabine as frst line therapy for advanced bladder cancer (and other urothelial cell carcinomas) Cardiff University 01/02/2008 31/12/2015 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory Committee

CRUKD/12/009: FIESTA: FGFR Inhibition in Epithelial Solid Tumours - AZD4547 in combination with gemcitabine and cisplatin: a phase Ib trial in advanced bladder cancer and other solid tumours University of Leeds 01/04/2012 30/06/2017 New Agents Committee - Trial Grant Application New Agents Committee

Chua, Dr Sue CRUKD/12/002: A phase I/II proof-of-concept study to compare the novel technique [124I]mIBG PET/CT to [123I]mIBG scintigraphy in paediatric patients with metastatic neuroblastoma Royal Marsden NHS Foundation Trust 01/12/2010 31/07/2017 New Agents Committee - DD Project Proposal New Agents CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Clamp, Dr Andrew Andrew.Clamp**[ta]**istie.nhs.uk

CRUK/10/030: ICON 8: An international 2-stage randomised trial of dose-fractionated CT compared to standard 3-weekly CT, following immediate primary surgery or as part of delayed primary surgery, for women with epithelial ovarian University College London 01/04/2011 31/03/2017 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

CRUK/13/023: ICON8B: A phase III randomised trial investigating the combination of dose-fractionated CT + bev compared to either strategy alone for the frstline treatment of women with ovarian cancer University College London 01/05/2014 30/04/2021 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Clarke, Professor Alan Modelling colorectal cancer in the mouse: assessing pathway synergies and antagonisms in vivo and validating therapeutic targets Cardiff University 01/07/2013 30/06/2018 Science Committee - Programme Award Science Committee

Clarke, Professor Paul p.r.clarke**[ta]**dee.ac.uk

Control of cell death during mitosis and in response to anti-mitotic drugs.University of Dundee 01/06/2012 31/05/2017 Science Committee - Programme Award Science Committee

Clifford, Professor Steven steve.clifford**[ta]**.ac.uk

Biomarker-driven individualisation of medulloblastoma therapy Newcastle University 01/04/2012 31/03/2017 Clinical and Translational Research Committee - Programme Award Science Committee

Coleman, Dr Helen h.coleman**[ta]**.ac.uk

The role of tumour vitamin D receptor expression, vitamin D related genetic variation and vitamin D supplement use in colorectal cancer survival Queen's University Belfast 01/01/2013 31/12/2015 Population Research Committee - Postdoctoral Fellowship Population Research Committee

Coleman, Professor Michel michel.coleman**[ta]**tm.ac.uk

Global surveillance of cancer survival (CONCORD-2) London School of Hygiene and Tropical Medicine 01/01/2013 31/12/2016 Population Research Committee - Programme Award Population Research Committee

Coleman, Professor Nicholas nc109**[ta]**.ac.uk

Viral and host mechanisms in cervical carcinogenesis: towards improved clinical management University of Cambridge 01/11/2011 31/10/2016 Science Committee - Programme Award Science Committee

Coleman, Professor Robert r.e.coleman**[ta]**feld.ac.uk

CRUKE/03/017: AZURE - Bone Health Sub-protocol: Bone health in breast cancer survivors following adjuvant bisphosphonate treatment University of Shefeld 01/12/2009 30/11/2015 Clinical Trials Awards & Advisory Committee - Endorsement - Late Phase Study Clinical Trials Awards & Advisory Committee

Collins, Dr Ian ian.collins**[ta]**.ac.uk

Preclinical development & CRUKD/16/002 A frst in human Phase I monotherapy trial of CCT245737, an oral selective Chk1 inhibitor, in solid tumours including NSCLC & pancreatic cancer Institute of Cancer Research 01/07/2013 31/12/2018 New Agents Committee - DD Project Proposal New Agents Committee

Collis, Dr Spencer s.collis**[ta]**feld.ac.uk

The identifcation and characterisation of novel genome maintenance factors University of Shefeld 01/09/2010 31/08/2016 New Investigator Committee - Senior Cancer Research Fellowship New Investigator CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Cook, Professor Gordon g.cook**[ta]**ds.ac.uk

CRUK/06/018: A UK myeloma forum phase III RCT in relapsed myeloma to assess the role of a second highdose procedure and autologous stem cell transplant, compared to low-dose consolidation therapy University of Leeds 01/09/2006 31/12/2017 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Cook, Dr Simon simon.cook**[ta]**raham.ac.uk

Understanding and overcoming resistance to MEK1/2 inhibitors in tumour cells Babraham Institute 01/01/2013 31/12/2016 Biological Sciences Committee - Project Award Science Committee

Coombes, Professor Raoul New Approaches to Reverse Endocrine Resistance in Breast Cancer Imperial College London 01/10/2010 30/09/2015 Science Committee - Programme Award Science Committee

Copson, Dr Ellen E.Copson**[ta]**on.ac.uk

Know Your Numbers (KYN): Adding Primary Prevention to the NHS Breast Screening Programme University of Southampton 01/10/2014 31/01/2016 Population Research Committee - BUPA Foundation Fund - Innovation Grant Population Research Committee

Corrie, Dr Pippa pippa.corrie**[ta]**enbrookes.nhs.uk

CRUK/06/014: ****AST-M: A randomised trial evaluating the VEGF inhibitor, Bevacizumab (Avastin®), as adjuvant therapy following resection of AJCC stage IIB (T3bN0M0 & T4aN0M0), IIC (T4bN0M0) and III (TxN1- 3M0) cutaneous melanoma.Cambridge University Hospitals NHS Trust 01/01/2011 31/12/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee